What is nmnh manufacturer ?

NMNH is "reduced Beta-nicotinamide mononucleotide", which is the reduced form of NMN with the CAS NO. of 108347-85-9 and molecular formula of C11H17N2O8P. Reduced β-NMN, NMNH (reduced nicotinamide mononucleotide) is a new and potent NAD+ precursor. It is a new form of NMN that can increase NAD levels to even higher levels. In general, there are three main manufacture methods for NMNH preparation utilized by NMNH manufacturers in the world such as chemical or enzymatic synthesis, and fermentation biosynthesis. And at present, the NMNH manufacturers are located worldwide including China, America, Japan and German.

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Why Choose BONTAC?

Advantages of NMNH

NMNH: 1. “Bonzyme” Whole-enzymatic method, environmental-friendly, no harmful solvent residues manufacturing powder. 2. Bontac is a very first manufacture in the world to produce the NMNH powder on the level of high purity, stability. 3. Exclusive “Bonpure” seven-step purification technology, high purity（up to 99%) and stability of production of NMNH powder 4. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products of NMNH powder 5. Provide one-stop product solution customization service

Advantages of NADH

NADH: 1. Bonzyme whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Exclusive Bonpure seven-step purification technology, purity up higher than 98 % 3. Special patented process crystal form, higher stability 4. Obtained a number of international certifications to ensure high quality 5. 8 domestic and foreign NADH patents, leading the industry 6. Provide one-stop product solution customization service

Advantages of NAD

NAD:　 1. “Bonzyme” Whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Stable supplier of 1000+ enterprises around the world 3. Unique “Bonpure” seven-step purification technology, higher product content and higher conversion rate 4. Freeze drying technology to ensure stable product quality 5. Unique crystal technology, higher product solubility 6. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products

Advantages of MNM

NMN:　 1. “Bonzyme”Whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Exclusive“Bonpure”seven-step purification technology, high purity（up to 99.9%) and stability 3. Industrial leading technology: 15 domestic and international NMN patents 4. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products 5. Multiple in vivo studies show that Bontac NMN is safe and effective 6. Provide one-stop product solution customization service 7. NMN raw material supplier of famous David Sinclair team of Harvard University

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Bontac Bio-Engineering (Shenzhen) Co., Ltd. (hereafter referred to as BONTAC) is a high-tech enterprise established in July 2012. BONTAC integrates R&D, production and sales, with enzyme catalysis technology as the core and coenzyme and natural products as main products. There are six major series of products in BONTAC, involving coenzymes, natural products, sugar substitutes, cosmetics, dietary supplements and medical intermediates.

As the leader of the global NMN industry, BONTAC has the first whole-enzyme catalysis technology in China. Our coenzyme products are widely used in health industry, medical & beauty, green agriculture, biomedicine and other fields. BONTAC adheres to independent innovation, with more than 170 invention patents. Different from the traditional chemical synthesis and fermentation industry, BONTAC has advantages of green low-carbon and high-value-added biosynthesis technology. What’s more, BONTAC has established the first coenzyme engineering technology research center at the provincial level in China which also is the sole in Guangdong Province.

In the future, BONTAC will focus on its advantages of green, low-carbon and high-value-added biosynthesis technology, and build ecological relationship with academia as well as upstream/downstream partners, continuously leading the synthetic biological industry and creating a better life for human beings.

The Chinese name of NMNH is "reduced nicotinamide mononucleotide". NMNH is an amorphous yellow powder. NMNH increases NAD+ levels faster and at a higher concentration, on average 5 times that of NMN. NMNH has been industrialized and has a purity of ≥99%. It is available in two forms: free acid and sodium salt.

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User Reviews

What users say about BONTAC

BONTAC is a reliable partner that we have been working with for many years. The purity of their coenzyme is very high. Their COA can achieve relatively high test results.

Front

I discovered BONTAC in 2014 because David's article in cell about NAD and NMN related showed that he used BONTAC's NMN for his experimental material. Then we found them in China. After so many years of cooperation, I think it is a very good company.

Hanks

I think green, healthy and high purity are the advantages of BONTAC's products compared with others. I still work with them to this day.

Phillip

In 2017, we chose BONTAC's coenzyme, during which our team encountered many technical problems and consulted their technical team, which were able to give us good solutions. Their products are shipped very fast and they work more efficiently.

Gobbs

Frequently Asked Question

Do you have any question?

What is the mechanism of NADH powder of Action?

NMNH also proved more effective than NMN in raising NAD+ levels in a variety of tissues when administered at the same concentration, confirming the results observed in cell lines. The data presented in this study also corroborate the evidence that NAD+ boosters protect against different models of acute kidney injury, and place NMNH as a great alternative intervention to other NAD+ precursors to reduce tubular damage and accelerate recovery.

What are the challenging in marketing for NMNH manufacturer?

To overcome the limitations of the current repertoire of NAD+ enhancers, other molecules with a more pronounced effect on the NAD+ intracellular pool are desired. This has stimulated us to investigate the use of the reduced form of nicotinamide mononucleotide (NMNH) as an NAD+ enhancer. There is very scarce information about the role of this molecule in cells. In fact, only one enzymatic activity has been described to produce NMNH. This is the NADH diphosphatase activity of the human peroxisomal Nudix hydrolase hNUDT1232 and the murine mitochondrial Nudt13.33 It has been postulated that, in cells, NMNH would be converted to NADH via nicotinamide mononucleotide adenylyl transferases (NMNATs).34 However, both NMNH production by Nudix diphosphatases and its use by NMNATs for NADH synthesis have only been described in vitro using isolated proteins, and how NMNH participates in cellular NAD+ metabolism remains unknown.

How to choose a real NMNH manufacturer?

First, inspect the factory. After some screening, NMNH companies that directly face consumers pay more attention to brand building. Therefore, for a good brand, quality is the most important thing, and the first thing to control the quality of raw materials is to inspect the factory. Bontac company actually manufacturing NMNH powder of high quality with the caterias of SGS. Secondly, the purity is tested. Purity is one of the most important parameters of NMN powder. If high purity NMNH cannot be guaranteed, the remaining substances are likely to exceed the relevant standards. As the attached certificates demonstrates that the NMNH powder produced by Bontac reach the purity of 99%. Finally, a professional test spectrum is needed to prove it. Common methods for determining the structure of an organic compound include Nuclear Magnetic Resonance Spectroscopy (NMR) and high-resolution mass spectrometry (HRMS). Usually through the analysis of these two spectra, the structure of the compound can be preliminarily determined.

Our updates and blog posts

02 Apr

Congratulation! BONTAC gains four more honors in health industry

Introduction On March 28, 2024, Digital Health and Precise Nutrition Forum & Annual Conference of Health Industry in 2023 is held in Shenzhen, China. By virtue of the technical innovation in synthetic biology, far-reaching industry impact and positive commitment to social responsibility, BONTAC has been awarded 4 more honors in the heath industry, namely the "The Benchmarking Enterprise of Shenzhen Health Industry in 2023", "The Most Valuable Investment Enterprise of Shenzhen Health Industry in 2023", "Special Contribution Award for Shenzhen Health Industry in 2023" and "The Excellent Case in Shenzhen Health Industry Development Report (2022)". About Digital Health and Precise Nutrition Forum & Annual Conference of Health Industry in 2023 This conference is organized by Shenzhen Health Industry Alliance, Shenzhen Association for the Development & Promotion of Health Industry and Shenzhen Health Care Association, aiming to award and recognize the paragons in the health industry who make great contributions with their practical actions. They represent the top level and mainstream of Shenzhen in health industry. Evaluation criteria for two of the awards As for “The Most Valuable Investment Enterprise of Shenzhen Health Industry in 2023", one should be equipped with: * Market share, brand impact and technical innovation ability * Explicit goal, customer demand and operation means * Leading technology, products or services * Management team with abundant experience and professional ability For the Benchmarking Enterprise of Shenzhen Health Industry in 2023, the selected enterprises should have: * Certain industry impacts * Achievement in scientific innovation, intellectual property, etc. * Active participation in the drafting of international/national/industry standard * An efficient and professional team * Positive commitment to the social responsibility Professor Zhang’s speech in round-table dialogue Professor Zhang, the chief scientist and founder in BONTAC, has been invited to participate in the round-table dialogue themed by “Digitization Empowers Nutrition and Health”. She shares profound and unique insights upon the research and practice of coenzyme raw materials in the field of precise nutrition. “BONTAC realizes the efficient synthesis and precise application of coenzyme raw materials in the fields such as food, agriculture and animal nutrition through deep integration of big data with AI technology”, Professor Zhang said. “We not only focus on the extensive use of coenzyme raw materials, but also emphasize their safety and function, with the purpose of satisfying everyone's demand on precise nutrition as well as promoting the continuous innovation and development of the health industry. Novel trend towards health industry Under the guidance of “Health China” strategy, there is an increasing trend towards to the deep integration of digital industry with health industry in current society. The reform of digital technology opens up unprecedented opportunities for the health industry, driving the intelligence, precision and personalization of health. In Shenzhen, a new blueprint for the high-quality development of “20+8” industry clusters (top 20 strategic emerging industrial clusters and 8 industries of the future) has been plotted in 2023. With the continuous optimization of industry structure, the health industry in Shenzhen has been developed rapidly, which infuses new energy for the economy and provides solid support for the citizen’s health and well-being. BONTAC as a driver of health and well-being BONTAC has been dedicated to the R&D, manufacture and sale of raw materials for coenzyme and natural products since 2012, who adheres to adopt the innovation-driven scientific strategy, with more than 170 invention patents, making great contributions to the health industry. Strikingly, a independent platform for directed evolution has been established in BONTAC, where premium enzyme species can be screened by AI to provide strong support for the production of high-quality coenzyme raw materials, driving the integration of digital industry with health industry. In 2024, BONTAC will continue to stick to our mission of “Green Bio-Tech, Healthier and Better Life!” and actively respond to the appeal in “Outline of the Program for Health China 2030”, promoting the deep integration of synthetic biology with health industry and constructing a better health service system.

30 Apr

Nourishing Wellness: BONTAC as a Leading Raw Material Supplier of Supplements

Nourishing Wellness: BONTAC as a Leading Raw Material Supplier of Supplements As a prominent raw material supplier of supplements, BONTAC is dedicated to developing and delivering premium products that promote health and well-being through innovative formulations and exceptional quality. We are committed to developing and delivering premium raw materials that fuel the success of your health and wellness products. With our focus on technical innovation, comprehensive business coverage, and dedicated technical support, we stand out as a leading partner for your raw material needs. Expertise in Nutraceutical Formulations BONTAC boasts a team of experts who excel in the development of nutraceutical formulations. Our blend of scientific knowledge and creativity enables us to create effective and advanced formulations that meet the highest standards of quality and efficacy. Through rigorous research and stringent quality control measures, we ensure that our raw materials contribute to the optimal results and success of your supplements. Diverse Range of Nutraceutical Products Deepening our understanding of cellular rejuvenation has been a core focus at BONTAC. We delve into various scientific disciplines, from molecular biology and genetics to epigenetics and regenerative medicine, to unravel the intricate processes that govern cellular aging and rejuvenation. Armed with this knowledge, we develop cutting-edge raw materials that promote cellular rejuvenation, allowing your products to tap into the body's natural ability to restore and regenerate itself. A Diverse Range of Nutraceutical Solutions Exploring BONTAC's extensive range of nutraceutical raw materials reveals a diverse array of products tailored to address various health needs. From immune support and stress management to dietary supplements and performance enhancers, each raw material is carefully crafted to deliver specific benefits. Our innovative ingredients, unique formulations, and proven efficacy in supporting overall health and wellness set our nutraceutical offerings apart from the competition. Partnering with BONTAC for Nutraceutical Excellence By partnering with BONTAC, businesses in the supplements industry can access customized strategies and high-quality raw materials that align with their health and wellness initiatives. Our dedicated technical support team will guide you in selecting the right raw materials and seamlessly integrating them into your product offerings. With BONTAC as your trusted partner, you can leverage our expertise, technical innovations, and extensive business coverage to elevate your product lines and provide exceptional value to your customers. Conclusion In conclusion, BONTAC's position as a leading raw material supplier of nutraceuticals stems from our unwavering commitment to excellence, technical innovation, and exceptional raw materials. By choosing BONTAC as your preferred supplier, you gain access to our expertise, quality raw materials, and dedication to helping your nutraceutical business thrive. Partner with us today and unlock the full potential of your health and wellness products.

30 Apr

Elevating Wellness: BONTAC Advanced Raw Materials for Cellular Health Supplements

Elevating Wellness: BONTAC Advanced Raw Materials for Cellular Health Supplements In today's fast-paced world, the quest for optimal health and wellness has led to a surge in the demand for high-quality cellular health supplements. At BONTAC, we specialize in crafting advanced raw materials that cater to the intricate needs of cellular health, promoting vitality and resilience at the core level of the body. Cutting-Edge Formulations for Cellular Health At BONTAC, our team of experts dedicates itself to pushing the boundaries of cellular nourishment through innovative approaches and meticulous formula development processes. Our advanced formulations are designed to enhance cellular function, supporting overall well-being and longevity through targeted nutritional support. At BONTAC, we recognize that every person's metabolism-boosting journey is unique, and we strive to provide a diverse range of products that cater to a wide spectrum of needs and preferences. Whether it's supporting energy production, promoting efficient nutrient utilization, or enhancing metabolism-boosting flexibility, our comprehensive lineup of metabolism-boosting products is designed to empower individuals to take control of their metabolism-boosting well-being. Unlocking the Benefits of Cellular Health Supplements BONTAC raw materials for cellular health supplements are carefully crafted to strengthen cellular resilience, boost energy metabolism, and promote optimal cell function. By incorporating the latest scientific advancements, our products can fortify the body at the cellular level, offering a comprehensive approach to enhancing health and vitality. Partnering with BONTAC for Cellular Wellness Solutions When businesses partner with BONTAC, they gain access to tailored strategies for cellular health, backed by our expertise in the field. Our commitment to technical innovation ensures that our products continually evolve to meet the changing needs of our customers. Through collaboration with BONTAC, businesses can tap into our comprehensive business coverage and strengthen their health offerings with our advanced cellular health supplements. By choosing BONTAC's metabolism-boosting products, you are not only investing in your health but also aligning yourself with a company that is dedicated to advancing the field of metabolism-boosting science. With our unwavering commitment to quality, innovation, and customer satisfaction, we invite you to join us on this transformative journey towards optimal metabolism-boosting health and a vibrant, fulfilling life. Conclusion Embark on a transformative journey towards enhanced health and longevity with BONTAC state-of-the-art raw materials for cellular health supplements. Our commitment to excellence, technical support, and innovation sets us apart in the industry, ensuring that our products meet or even exceed the expectations of our partners and customers. Join us in optimizing cellular wellness and unlocking the full potential of health with BONTAC by your side. In conclusion, BONTAC advanced raw materials for cellular health supplements demonstrate our dedication to providing outstanding products that prioritize the well-being of our customers. If you require further information or assistance, please do not hesitate to reach out to our team.